ADB-5'F-BUTINACA
ADB-5'F-BUTINACA[edit | edit source]
ADB-5'F-BUTINACA is a synthetic cannabinoid that has been used as a designer drug. It is a potent agonist of the cannabinoid receptors, which are part of the endocannabinoid system in the human body. This compound is part of a class of synthetic cannabinoids that are often found in products marketed as "herbal incense" or "synthetic marijuana."
Chemical Structure and Properties[edit | edit source]
ADB-5'F-BUTINACA is chemically classified as an indazole-based synthetic cannabinoid. Its structure includes a 5-fluoropentyl chain, which is a common feature in many synthetic cannabinoids, contributing to its high potency. The chemical formula of ADB-5'F-BUTINACA is C20H28FN3O3, and it has a molecular weight of 377.46 g/mol.
The compound is known for its high affinity for the CB1 and CB2 receptors, which are the primary targets of cannabinoids in the body. This high affinity is responsible for its potent psychoactive effects.
Pharmacology[edit | edit source]
As a synthetic cannabinoid, ADB-5'F-BUTINACA acts as a full agonist at the CB1 and CB2 receptors. These receptors are part of the G protein-coupled receptor family and are involved in a variety of physiological processes, including pain sensation, mood regulation, and appetite.
The activation of these receptors by ADB-5'F-BUTINACA can lead to effects similar to those of tetrahydrocannabinol (THC), the active component of cannabis. However, synthetic cannabinoids like ADB-5'F-BUTINACA can be significantly more potent than THC, leading to a higher risk of adverse effects.
Legal Status[edit | edit source]
Due to its potential for abuse and lack of medical use, ADB-5'F-BUTINACA has been classified as a controlled substance in many jurisdictions. The legal status of synthetic cannabinoids can vary widely between countries and even within regions of the same country.
Health Effects and Risks[edit | edit source]
The use of ADB-5'F-BUTINACA has been associated with a range of adverse health effects. These can include tachycardia, hypertension, nausea, vomiting, anxiety, hallucinations, and seizures. In severe cases, use of synthetic cannabinoids can lead to acute kidney injury and death.
The unpredictability of the effects of synthetic cannabinoids is partly due to the variability in the chemical composition of products sold as "synthetic marijuana." These products often contain a mixture of different synthetic cannabinoids, which can interact in unpredictable ways.
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