Actifed

Actifed

Actifed is a combination medication used to treat symptoms associated with the common cold, allergies, or other respiratory illnesses. It is primarily composed of an antihistamine and a decongestant, which work together to alleviate nasal congestion, sneezing, and runny nose.

Composition

Actifed typically contains the following active ingredients:

• Triprolidine: An antihistamine that helps reduce the effects of the natural chemical histamine in the body, which can cause symptoms such as sneezing, itching, watery eyes, and runny nose.
• Pseudoephedrine: A decongestant that shrinks blood vessels in the nasal passages, leading to decreased congestion and easier breathing.

Mechanism of Action

The combination of triprolidine and pseudoephedrine in Actifed works by targeting different pathways involved in the body's response to allergens and infections:

• Triprolidine blocks the action of histamine at H1 receptors, thereby reducing allergic symptoms.
• Pseudoephedrine acts on adrenergic receptors to cause vasoconstriction, reducing swelling and congestion in the nasal passages.

Indications

Actifed is indicated for the relief of symptoms associated with:

• Common cold
• Allergic rhinitis
• Sinusitis

Contraindications

Actifed should not be used in individuals with:

• Severe hypertension or coronary artery disease
• Known hypersensitivity to any of its components
• Concurrent use of monoamine oxidase inhibitors (MAOIs)

Side Effects

Common side effects of Actifed may include:

• Drowsiness
• Dizziness
• Dry mouth
• Nervousness

Serious side effects are rare but can include:

• Increased blood pressure
• Palpitations
• Severe allergic reactions

Dosage and Administration

Actifed is usually taken orally, with or without food. The dosage depends on the age of the patient and the severity of symptoms. It is important to follow the prescribed dosage and not exceed the recommended amount to avoid potential side effects.

Precautions

Patients should be advised to:

• Avoid alcohol and other central nervous system depressants while taking Actifed.
• Use caution when driving or operating machinery, as the medication can cause drowsiness.
• Consult a healthcare provider if symptoms persist or worsen.

Also see

• Antihistamine
• Decongestant
• Common cold
• Allergic rhinitis