Actinic Prurigo

Actinic Prurigo is a rare, chronic skin condition characterized by intensely itchy, red bumps and blisters that appear after exposure to sunlight. This condition is also known as Hereditary Polymorphous Light Eruption and is more common in people of Native American descent.

Etiology

The exact cause of Actinic Prurigo is unknown, but it is believed to be an abnormal immune response to sunlight. It is also thought to have a genetic component, as it often runs in families. Genetic factors may make some people more susceptible to developing this condition.

Symptoms

The primary symptom of Actinic Prurigo is a skin rash that develops after exposure to sunlight. This rash can appear anywhere on the body, but it is most commonly found on areas of the skin that are frequently exposed to the sun, such as the face, neck, and hands. The rash typically consists of small, itchy bumps and blisters that can become crusty and scaly over time. Other symptoms may include lip inflammation, eye irritation, and conjunctivitis.

Diagnosis

Diagnosis of Actinic Prurigo is typically based on the patient's symptoms and medical history. A physical examination of the skin and a review of the patient's exposure to sunlight can also help in the diagnosis. In some cases, a skin biopsy may be performed to rule out other conditions.

Treatment

There is currently no cure for Actinic Prurigo, but treatments are available to manage the symptoms. These may include topical corticosteroids to reduce inflammation and itching, as well as phototherapy to desensitize the skin to sunlight. In severe cases, systemic medications such as antimalarials may be used. Patients are also advised to limit their exposure to sunlight and to use sun protection measures such as wearing protective clothing and using sunscreen.

Prognosis

The prognosis for Actinic Prurigo varies. Some people may experience a decrease in symptoms over time, while others may have persistent symptoms that require ongoing treatment. It is important for patients to work closely with their healthcare provider to manage their symptoms and to prevent complications.

See also

• Photodermatitis
• Polymorphous light eruption
• Sun allergy

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