Adducted thumb syndrome

Adducted thumb syndrome
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Synonyms	Adducted thumb-clubfoot syndrome
Pronounce	N/A
Specialty	N/A
Symptoms	Adducted thumb, clubfoot, cleft palate, scoliosis
Complications	N/A
Onset	Congenital
Duration	Lifelong
Types	N/A
Causes	Genetic mutation
Risks	Family history
Diagnosis	Clinical examination, genetic testing
Differential diagnosis	N/A
Prevention	N/A
Treatment	Orthopedic surgery, physical therapy
Medication	N/A
Prognosis	N/A
Frequency	Rare
Deaths	N/A

Adducted thumb syndrome, also known as adducted thumb-clubfoot syndrome, is a rare genetic disorder characterized by the presence of adducted thumbs, clubfoot, and other associated anomalies. This condition is congenital, meaning it is present at birth, and is caused by mutations in specific genes.

Signs and Symptoms

Individuals with adducted thumb syndrome typically present with:

• Adducted thumb: The thumb is held in a flexed position across the palm.
• Clubfoot: A deformity where the foot is twisted out of shape or position.
• Cleft palate: An opening or split in the roof of the mouth.
• Scoliosis: A sideways curvature of the spine.

Causes

Adducted thumb syndrome is primarily caused by genetic mutations that affect the development of the limbs and other parts of the body. These mutations can be inherited from a parent or occur spontaneously.

Diagnosis

Diagnosis of adducted thumb syndrome is based on a combination of clinical examination and genetic testing. A healthcare provider will assess the physical signs and may order genetic tests to confirm the diagnosis.

Treatment

Treatment for adducted thumb syndrome often involves a multidisciplinary approach, including:

• Orthopedic surgery: To correct deformities such as clubfoot.
• Physical therapy: To improve mobility and function.

Prognosis

The prognosis for individuals with adducted thumb syndrome varies depending on the severity of the symptoms and the success of treatment interventions. Early diagnosis and treatment can improve outcomes.

See Also

• Genetic disorder
• Congenital anomaly
• Orthopedic surgery

External Links

• [Genetic and Rare Diseases Information Center](https://rarediseases.info.nih.gov/)