Alexander Glenny

British immunologist

Alexander Thomas Glenny (18 September 1882 – 5 October 1965) was a British immunologist known for his pioneering work in the development of vaccines, particularly the diphtheria toxoid vaccine. His contributions to immunology have had a lasting impact on public health.

Early life and education

Alexander Glenny was born in Cambridge, England. He attended the University of Cambridge, where he studied natural sciences. His interest in immunology was sparked during his undergraduate studies, leading him to pursue a career in medical research.

Career

Work on diphtheria

Alexander Thomas Glenny in his lab coat

Glenny's most notable contribution to medicine was his work on the diphtheria toxoid vaccine. In the early 20th century, diphtheria was a major cause of illness and death among children. Glenny, along with his colleagues, developed a method to inactivate the diphtheria toxin using formaldehyde, creating a safe and effective vaccine. This work laid the foundation for the widespread use of toxoid vaccines.

Other contributions

In addition to his work on diphtheria, Glenny made significant contributions to the understanding of immunological memory and the adjuvant effect. He was one of the first to describe the phenomenon of adjuvants, substances that enhance the body's immune response to an antigen. His research in this area helped to improve the efficacy of vaccines.

Legacy

Glenny's work has had a profound impact on public health, leading to the near eradication of diphtheria in many parts of the world. His research on adjuvants continues to influence vaccine development today. Glenny's dedication to immunology and his innovative approach to vaccine development have earned him a place among the most respected figures in medical research.

Related pages

• Immunology
• Vaccine
• Diphtheria
• Adjuvant