Alglucerase

Alglucerase was a biopharmaceutical drug for the treatment of Gaucher's disease. It was a modified form of human Î²-glucocerebrosidase enzyme, where the non-reducing ends of the oligosaccharide chains have been terminated with mannose residues. Ceredase is the trade name of a citrate buffered solution of alglucerase that was manufactured by Genzyme Corporation from human placental tissue. It is given intravenously in the treatment of Type 1 Gaucher's disease. This was the first drug approved as an enzyme replacement therapy.

[[Category:Drugs

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