Allethrins

From WikiMD's Wellnesspedia

Allethrins are a pair of related synthetic compounds used in insecticides. They are pyrethroids, a type of cytotoxic molecule that kills by disrupting the function of the nervous system. Allethrins were first synthesized in the United States in 1949 and are commonly used in household insecticides such as mosquito coils. They are also the primary insecticidal component in some types of insect-repelling candles.

Chemistry[edit | edit source]

Allethrins are part of the pyrethroid family of insecticides, which are synthetic analogs of pyrethrins, natural insecticides derived from the flowers of Chrysanthemum cinerariifolium. Pyrethroids, including allethrins, are often preferred for insecticide use because of their high effectiveness and low toxicity to humans and animals.

Allethrins are esters of chrysanthemic acid. They are produced industrially by the esterification of chrysanthemic acid with allethrolone.

Mode of action[edit | edit source]

Allethrins exert their insecticidal effects by disrupting the function of the nervous system in insects. They bind to the voltage-gated sodium channels in nerve cell membranes, preventing normal function and causing paralysis and death. This mode of action is similar to that of other pyrethroids.

Safety[edit | edit source]

While allethrins are toxic to insects, they have low toxicity in mammals, including humans. However, they can cause some adverse health effects if improperly handled or ingested. Symptoms of exposure can include nausea, headache, and skin irritation. In severe cases, seizures may occur.

Environmental impact[edit | edit source]

Like other pyrethroids, allethrins are not very soluble in water and tend to bind strongly to soil particles. This means they do not typically leach into groundwater. However, they are toxic to aquatic organisms and can cause environmental harm if they enter water bodies.

See also[edit | edit source]

Resources[edit source]

Latest articles - Allethrins

PubMed
Clinical trials
UpToDate

AI tools[edit source]

Generative AI tools and links to learn more on Allethrins: ChatGPT - Bing Chat - Google Gemini. (caution advised).


Wiki.png

Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD


Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD

WikiMD is not a substitute for professional medical advice. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.


Contributors: Admin, Prab R. Tumpati, MD