Alpha-Tocotrienol

Alpha-Tocotrienol is one of the eight members of the group known as vitamin E. This group consists of four tocopherols and four tocotrienols, all of which are fat-soluble antioxidants. Alpha-Tocotrienol is distinguished from the other forms of vitamin E by its unsaturated side chain.

Chemical Structure

Alpha-Tocotrienol, like all tocotrienols, has a chromanol ring, with an unsaturated side chain. The designation "alpha" means that the hydroxyl group on the chromanol ring is in the R configuration at the 2 position, according to IUPAC rules for nomenclature of organic compounds.

Biological Role

Alpha-Tocotrienol has been found to have several biological roles. It is a potent antioxidant, protecting cell membranes from damage by free radicals. It also has anti-inflammatory properties, and can inhibit the activity of cyclooxygenase, an enzyme involved in inflammation.

Recent research has suggested that alpha-tocotrienol may also have neuroprotective effects. It has been found to prevent neuronal death in mouse models of stroke, and may also protect against neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.

Dietary Sources

Alpha-Tocotrienol is found in a variety of foods, including palm oil, rice bran oil, and barley. It is also available as a dietary supplement.

Health Benefits

The health benefits of alpha-tocotrienol are still being researched. However, it is known that as an antioxidant, it can protect against oxidative stress, which is implicated in a variety of diseases, including heart disease, cancer, and neurodegenerative diseases.

See Also

• Vitamin E
• Tocotrienol
• Antioxidant
• Neuroprotection

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