Aluminium nicotinate

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Aluminium Nicotinate[edit | edit source]

Chemical structure of Aluminium Nicotinate

Aluminium nicotinate is a chemical compound that consists of aluminium and nicotinic acid, also known as niacin or vitamin B3. It is used in various medical and pharmaceutical applications due to its properties as a vasodilator and its role in lipid metabolism.

Chemical Structure[edit | edit source]

Aluminium nicotinate is formed by the coordination of nicotinic acid molecules with an aluminium ion. The chemical structure can be represented by the formula Al(C_H_NO_)_, where each aluminium ion is coordinated with three nicotinate ions. The structure is depicted in the adjacent image.

Pharmacological Properties[edit | edit source]

Aluminium nicotinate is known for its ability to act as a vasodilator, which means it can widen blood vessels and improve blood flow. This property makes it useful in the treatment of conditions related to poor circulation. Additionally, nicotinic acid, a component of aluminium nicotinate, plays a crucial role in lipid metabolism, helping to lower cholesterol levels and reduce the risk of cardiovascular diseases.

Medical Applications[edit | edit source]

In the medical field, aluminium nicotinate is used for its vasodilatory effects to treat conditions such as peripheral artery disease and Raynaud's phenomenon. It is also investigated for its potential benefits in managing hyperlipidemia due to its ability to influence lipid profiles positively.

Safety and Side Effects[edit | edit source]

While aluminium nicotinate is generally considered safe when used appropriately, it may cause side effects in some individuals. Common side effects include flushing, itching, and gastrointestinal discomfort. It is important for patients to consult with healthcare professionals before using aluminium nicotinate, especially if they have pre-existing medical conditions or are taking other medications.

Related Compounds[edit | edit source]

Aluminium nicotinate is related to other compounds that contain nicotinic acid, such as niacinamide and inositol hexanicotinate. These compounds also have applications in medicine and nutrition, particularly in the management of cholesterol levels and cardiovascular health.

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Contributors: Prab R. Tumpati, MD