Amelometasone

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Amelometasone is a type of corticosteroid, specifically a glucocorticoid, used in the treatment of various skin conditions. It is a synthetic steroid that has anti-inflammatory, antipruritic, and vasoconstrictive properties.

Pharmacology[edit | edit source]

Amelometasone works by decreasing the number of immune cells that cause inflammation and allergy. It does this by inhibiting the release of inflammatory mediators from eosinophils and reducing the metabolism of arachidonic acid, which leads to decreased formation of prostaglandins and leukotrienes.

Uses[edit | edit source]

Amelometasone is primarily used in the treatment of dermatitis, eczema, psoriasis, and other inflammatory skin conditions. It is also used to treat allergic reactions, and other conditions that cause itching and redness of the skin.

Side Effects[edit | edit source]

Like other corticosteroids, amelometasone can cause a number of side effects. These can include skin thinning, acne, rosacea, and hyperpigmentation. In rare cases, it can cause systemic side effects such as Cushing's syndrome, hypertension, and glucose intolerance.

Precautions[edit | edit source]

Patients using amelometasone should avoid exposure to sunlight or artificial UV light, as this can increase the risk of skin damage. It should not be used on broken or infected skin, or on areas of the skin affected by tuberculosis, syphilis, or chickenpox.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD