Ampelopsin

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Ampelopsin

Ampelopsin, also known as dihydromyricetin, is a flavanonol, a type of flavonoid. It is found in various plants, including the Japanese raisin tree (Hovenia dulcis) and some species of the genus Ampelopsis. Ampelopsin has been studied for its potential health benefits and pharmacological properties.

Chemical Structure and Properties[edit | edit source]

Ampelopsin has the chemical formula C15H12O8 and a molecular weight of 320.25 g/mol. It is characterized by its three-ring structure with multiple hydroxyl groups, which contribute to its antioxidant properties.

Sources[edit | edit source]

Ampelopsin is primarily extracted from the Japanese raisin tree (Hovenia dulcis) and various species of the genus Ampelopsis. These plants have been traditionally used in East Asian medicine for their purported health benefits.

Potential Health Benefits[edit | edit source]

Ampelopsin has been the subject of research for its potential health benefits, including:

  • Antioxidant properties: Ampelopsin is known to scavenge free radicals, which can help in reducing oxidative stress in the body.
  • Anti-inflammatory effects: Studies suggest that ampelopsin may help in reducing inflammation by inhibiting certain inflammatory pathways.
  • Hepatoprotective effects: Ampelopsin has been studied for its potential to protect the liver from damage caused by toxins and alcohol.
  • Neuroprotective effects: Research indicates that ampelopsin may have protective effects on the brain and could be beneficial in conditions like Alzheimer's disease.

Pharmacology[edit | edit source]

Ampelopsin is absorbed in the gastrointestinal tract and metabolized in the liver. It is known to interact with various cellular pathways, including those involved in oxidative stress and inflammation. The exact mechanisms of its pharmacological effects are still under investigation.

Traditional Uses[edit | edit source]

In traditional Chinese medicine, ampelopsin-containing plants like the Japanese raisin tree have been used to treat various ailments, including hangovers, liver disorders, and fever.

Research and Studies[edit | edit source]

Numerous studies have been conducted to explore the potential health benefits of ampelopsin. These studies have primarily focused on its antioxidant, anti-inflammatory, hepatoprotective, and neuroprotective properties. However, more research is needed to fully understand its mechanisms and potential therapeutic applications.

See Also[edit | edit source]

References[edit | edit source]

External Links[edit | edit source]


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Contributors: Prab R. Tumpati, MD