Anileridine phosphate

Anileridine Phosphate is a synthetic opioid analgesic drug, chemically classified as a piperidine derivative. It was first synthesized in the mid-20th century and is used in the management of moderate to severe pain.

History

Anileridine Phosphate was first synthesized in the 1950s by the pharmaceutical company Eli Lilly. It was developed as part of a series of analgesics which also included meperidine and pethidine. The drug was approved by the FDA in the United States in 1957.

Pharmacology

Anileridine Phosphate acts on the central nervous system (CNS) to provide pain relief. It is a potent agonist at the mu-opioid receptor, which is primarily responsible for the analgesic effects of opioids. The drug also has some activity at the kappa-opioid receptor, which can contribute to analgesia as well as side effects such as sedation and dysphoria.

Clinical Use

Anileridine Phosphate is used in the management of moderate to severe pain. It can be used for both acute and chronic pain conditions. The drug is typically administered via injection, although oral formulations are also available.

Side Effects

Common side effects of Anileridine Phosphate include nausea, vomiting, constipation, and drowsiness. Like other opioids, the drug also carries a risk of opioid dependence and opioid overdose.

See Also

• Opioid
• Pain management
• Opioid dependence
• Opioid overdose