Anti-obesity

Anti-obesity medication or weight loss drugs are pharmacological agents that reduce or control weight. These drugs alter one of the fundamental processes of the human body, weight regulation, by altering either appetite, or absorption of calories. The main treatment modalities for overweight and obesity are dieting and physical exercise.

Mechanism of action

Anti-obesity medication work by altering the body's natural processes, often targeting the metabolism or suppressing the appetite. Some medications, like orlistat, block the absorption of fat or carbohydrates, which can lead to weight loss. Others, like sibutramine, suppress the appetite, making the individual feel full and eat less.

History

The use of anti-obesity medication dates back to the ancient Greeks and Romans. It was not until the 1920s and 1930s, however, that new treatments began to appear. Based on its effectiveness for hypothyroidism, thyroid hormone became a popular treatment for obesity in eutrophic individuals, but it had no effect on excess weight.

Side effects

Like all medication, anti-obesity drugs have side effects. These can range from mild (like nausea, constipation, and dry mouth) to severe (like pulmonary hypertension and heart valve damage).

See also

• Obesity
• Dieting
• Physical exercise
• Weight loss

References

Anti-obesity Resources
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