Antidepressants in Japan

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Antidepressants in Japan are a class of medications used primarily to treat depression, but also for other mental health conditions. In Japan, the use of antidepressants has been influenced by cultural, societal, and medical factors unique to the country.

History[edit | edit source]

The history of antidepressants in Japan is marked by a late introduction compared to Western countries. The first antidepressant, iproniazid, was not introduced until 1958, several years after its introduction in the United States. This delay was due to a variety of factors, including societal stigma towards mental health disorders and a lack of understanding about the biological basis of depression.

Usage[edit | edit source]

The usage of antidepressants in Japan has increased significantly over the past few decades. This is due in part to a shift in societal attitudes towards mental health, as well as changes in the Japanese healthcare system that have made it easier for individuals to seek treatment for mental health disorders. Despite this increase, the usage of antidepressants in Japan remains lower than in many Western countries.

Types of Antidepressants[edit | edit source]

There are several types of antidepressants available in Japan, including Selective serotonin reuptake inhibitors (SSRIs), Serotonin and norepinephrine reuptake inhibitors (SNRIs), and Tricyclic antidepressants (TCAs). Each of these types of antidepressants works in a slightly different way to alleviate the symptoms of depression.

Cultural and Societal Factors[edit | edit source]

Cultural and societal factors have played a significant role in the use of antidepressants in Japan. Historically, there has been a strong stigma associated with mental health disorders in Japan, which has made it difficult for individuals to seek treatment. However, this stigma has been gradually decreasing, leading to an increase in the use of antidepressants.

Regulation[edit | edit source]

The regulation of antidepressants in Japan is overseen by the Pharmaceuticals and Medical Devices Agency (PMDA). The PMDA is responsible for ensuring the safety and efficacy of all medications sold in Japan, including antidepressants.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD