Antigenes

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Antigenes[edit | edit source]

Antigenes structure

Antigenes is a term used in immunology to describe substances that can induce an immune response in an organism. These substances are typically foreign to the body and can include proteins, polysaccharides, lipids, or nucleic acids. Antigenes play a crucial role in the immune system's ability to recognize and eliminate harmful pathogens.

Structure[edit | edit source]

The structure of antigenes can vary greatly depending on their composition. Proteins, for example, are composed of amino acids and can have complex three-dimensional structures. Polysaccharides, on the other hand, are composed of sugar molecules and can form linear or branched chains. Lipids are composed of fatty acids and can be found in various forms such as triglycerides or phospholipids. Nucleic acids, including DNA and RNA, are composed of nucleotides and have a double helix structure.

Function[edit | edit source]

Antigenes function by interacting with specific components of the immune system, known as antibodies or T cells. When an antigen enters the body, it is recognized by these immune cells through specific binding interactions. This recognition triggers a series of immune responses aimed at eliminating the antigen and preventing further harm to the organism.

Types of Antigenes[edit | edit source]

There are two main types of antigenes: exogenous antigenes and endogenous antigenes.

Exogenous antigenes are derived from sources outside the body, such as bacteria, viruses, or other foreign substances. These antigenes are typically captured by specialized cells of the immune system, such as dendritic cells, and presented to other immune cells for recognition and response.

Endogenous antigenes, on the other hand, are produced within the body. They can be derived from normal cellular processes or from abnormal cellular events, such as viral infections or cancer. Endogenous antigenes are presented to immune cells by infected or cancerous cells, triggering an immune response against these abnormal cells.

Importance in Immunity[edit | edit source]

Antigenes are crucial for the proper functioning of the immune system. They allow the immune system to distinguish between self and non-self, enabling the targeting and elimination of harmful pathogens while preserving the body's own cells and tissues.

The ability of antigenes to induce an immune response is exploited in various medical applications, such as vaccination. Vaccines contain weakened or inactivated forms of specific antigenes, which stimulate the immune system to produce a protective response. This response leads to the production of antibodies or memory T cells, providing long-term immunity against the targeted pathogen.

Conclusion[edit | edit source]

In summary, antigenes are substances that can induce an immune response in an organism. Their structure can vary depending on their composition, and they play a crucial role in the immune system's ability to recognize and eliminate harmful pathogens. Understanding the function and types of antigenes is essential for advancing our knowledge of immunology and developing effective strategies for disease prevention and treatment.

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Contributors: Prab R. Tumpati, MD