Aortic lymph nodes

Aortic lymph nodes are a group of lymph nodes that are located in the vicinity of the aorta, the main and largest artery in the human body. They play a crucial role in the immune system, helping to filter harmful substances and fight infections.

Anatomy

The aortic lymph nodes are divided into several groups, each named according to their location relative to the aorta. These include the preaortic, retroaortic, and paraaortic lymph nodes. The preaortic lymph nodes are located in front of the aorta, the retroaortic lymph nodes are located behind the aorta, and the paraaortic lymph nodes are located on either side of the aorta.

Function

The primary function of the aortic lymph nodes, like other lymph nodes in the body, is to produce and store cells that fight infection and disease. They do this by filtering the lymphatic fluid and trapping bacteria, viruses, and other harmful substances, which are then destroyed by special white blood cells known as lymphocytes.

Clinical significance

Aortic lymph nodes can become enlarged or inflamed in response to infection or disease, a condition known as lymphadenopathy. This can occur as a result of a local infection or it can be a sign of a more systemic condition, such as cancer or autoimmune disease. In particular, enlargement of the aortic lymph nodes can be a sign of abdominal or pelvic cancer.

See also

• Lymphatic system
• Lymph node
• Aorta