Aplasia
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Aplasia[edit | edit source]
Aplasia () originates from the Greek words a (indicating absence) and plasis (referring to molding or formation). This birth defect is characterized by the absence or defective development of an organ or tissue.[1][2]
Aplastic anemia, a prominent example, signifies the body's inability to produce blood cells. The condition can manifest at any age, resulting from a variety of causes.[1][2]
Etymology[edit | edit source]
The term "aplasia" is derived from Greek:
- a – Meaning "not" or "no"
- plasis – Denoting "molding" or "formation"
Examples of Aplasia[edit | edit source]
Aplasia can manifest in multiple ways, impacting different tissues and organs. Some notable instances include:
- Acquired pure red cell aplasia – A specific type of anemia affecting the red blood cells.
- Aplasia cutis congenita – Denotes the congenital absence of skin.
- Aplastic anemia – Represents a failure in blood cell production.
- Germ cell aplasia – Also recognized as the Sertoli cell-only syndrome.
- Radial aplasia – Absence or underdevelopment of the radial bone in the forearm.
- Thymic aplasia – Observed in DiGeorge syndrome and also naturally appears with the progressive loss of the immune system's functionality during advanced age.
Comparative Terminology[edit | edit source]
While "aplasia" indicates the absence of tissue or organ development, there are related terms that describe variations in development:
- Atrophy – Decrease in size of an already developed organ or tissue.
- Hyperplasia – Excessive proliferation of normal cells in normal tissue arrangement.
- Hypoplasia – Incomplete or underdevelopment of a tissue or organ.
- Neoplasia – Abnormal or uncontrolled growth, which can be benign or malignant.
List of biological development disorders[edit | edit source]
Disorder Name | Description | Affected Organ/System |
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Aplasia | Absence or defective development of an organ or tissue. | Various organs or tissues |
Hypoplasia | Incomplete or underdevelopment of a tissue or organ. | Various organs or tissues |
Polydactyly | Presence of extra fingers or toes. | Hands and Feet |
Cleft Palate | Opening or split in the roof of the mouth. | Oral cavity |
Spina Bifida | Birth defect where there is incomplete closing of the spine. | Spine |
Hydrocephalus | Buildup of fluid in the brain. | Brain |
References[edit | edit source]
- ↑ 1.0 1.1
- ↑ 2.0 2.1 "Stedman's > aplasia". Drugs.com. Retrieved 17 February 2010.
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