Apraclonidine
Apraclonidine is a medication used in the treatment of glaucoma, a condition that increases pressure in the eyes and can lead to vision loss. It is also used to prevent or control increases in intraocular pressure (IOP) after laser eye surgery. Apraclonidine is an alpha-2 adrenergic agonist, a type of drug that reduces the amount of fluid in the eyes, thereby reducing pressure.
Etymology[edit | edit source]
The term "apraclonidine" is derived from the chemical name "apraclonidine hydrochloride". The prefix "apra-" is derived from the Greek word "apra", meaning "away from", and "clonidine" is a common suffix used in the names of adrenergic agonists.
Pharmacology[edit | edit source]
Apraclonidine works by stimulating alpha-2 adrenergic receptors in the eye. This reduces the production of aqueous humor (the fluid in the eye) and increases the flow of aqueous humor out of the eye, thereby reducing intraocular pressure.
Usage[edit | edit source]
Apraclonidine is typically administered as eye drops. The usual dosage is one drop in the affected eye(s) three times a day. It is important to use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day.
Side Effects[edit | edit source]
Common side effects of apraclonidine include dry mouth, blurred vision, and a burning or stinging sensation in the eye. More serious side effects can include severe headaches, slow or irregular heartbeat, and depression. If any of these side effects occur, it is important to seek medical attention immediately.
Related Terms[edit | edit source]
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Contributors: Prab R. Tumpati, MD