Artificial blood

From WikiMD's Food, Medicine & Wellness Encyclopedia

Artificial Blood is a product made to act as a substitute for red blood cells. Due to certain circumstances, such as surgery, trauma, or diseases like anemia, a person's body may require extra blood. When donations of human blood are not available, or when a patient cannot accept human blood products, artificial blood can be used.

History[edit | edit source]

The concept of artificial blood dates back to the 17th century, with the experiments of Robert Boyle and Richard Lower. However, it was not until the 20th century that significant progress was made in this field. The first successful blood transfusion using artificial blood took place in 2002.

Types[edit | edit source]

There are two main types of artificial blood: hemoglobin-based oxygen carriers (HBOCs) and perfluorocarbon-based oxygen carriers (PFCs). HBOCs are made from either human or bovine hemoglobin, while PFCs are made from carbon and fluorine molecules.

Production[edit | edit source]

The production of artificial blood involves several steps. For HBOCs, the hemoglobin is first isolated and then chemically modified to prevent it from breaking down. For PFCs, the perfluorocarbon molecules are mixed with water and emulsifiers to create a stable emulsion.

Uses[edit | edit source]

Artificial blood is primarily used in the medical field, particularly in emergency medicine and surgery. It can also be used in research and in the military.

Advantages and Disadvantages[edit | edit source]

The main advantage of artificial blood is that it can be used when human blood is not available or cannot be used. It also does not carry the risk of transmitting blood-borne diseases. However, there are also disadvantages, such as the risk of allergic reactions and the high cost of production.

Future[edit | edit source]

Research is ongoing to improve the safety and effectiveness of artificial blood. Future developments may include the use of stem cells to produce artificial red blood cells.

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Contributors: Prab R. Tumpati, MD