Atherosclerosis Risk in Communities

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Atherosclerosis Risk in Communities[edit | edit source]

The Atherosclerosis Risk in Communities (ARIC) study is a long-term, ongoing epidemiological study designed to investigate the causes and outcomes of atherosclerosis and its clinical outcomes, including coronary heart disease, stroke, and heart failure. The study is conducted in four U.S. communities and involves a diverse cohort of participants.

Study Design[edit | edit source]

The ARIC study began in 1987 and involves a cohort of approximately 15,792 participants aged 45 to 64 years at baseline. The study is designed to explore the development of atherosclerosis and its risk factors over time. Participants undergo regular examinations and assessments, including medical history, physical examinations, and laboratory tests.

Objectives[edit | edit source]

The primary objectives of the ARIC study are to:

  • Investigate the natural history of atherosclerosis.
  • Identify risk factors associated with the development of atherosclerosis.
  • Examine the relationship between atherosclerosis and cardiovascular diseases such as coronary heart disease and stroke.
  • Study the genetic and environmental factors contributing to cardiovascular health.

Key Findings[edit | edit source]

The ARIC study has contributed significantly to the understanding of cardiovascular disease. Some key findings include:

  • The identification of novel risk factors for atherosclerosis, including certain lipoproteins and inflammatory markers.
  • Insights into the role of hypertension, diabetes, and smoking in the development of cardiovascular diseases.
  • The impact of lifestyle factors such as diet and physical activity on cardiovascular health.

Community Involvement[edit | edit source]

The ARIC study is conducted in four communities: Forsyth County, North Carolina; Jackson, Mississippi; suburban Minneapolis, Minnesota; and Washington County, Maryland. These communities were selected to provide a diverse representation of the U.S. population. Community involvement and engagement are crucial components of the study, ensuring participant retention and data quality.

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