Audenz
Audenz is a vaccine developed for the prevention of influenza A virus subtype H5N1, commonly known as avian influenza or bird flu. It is designed to protect against the H5N1 strain of the influenza virus, which has the potential to cause severe respiratory illness in humans and has a high mortality rate.
Development and Approval[edit | edit source]
Audenz was developed by Seqirus, a global leader in influenza prevention. The vaccine was approved by the United States Food and Drug Administration (FDA) in 2020 for use in individuals 6 months of age and older. The approval was based on clinical trials that demonstrated the vaccine's safety and efficacy in producing an immune response against the H5N1 virus.
Composition[edit | edit source]
Audenz is an inactivated influenza vaccine, meaning it contains a virus that has been killed and cannot cause disease. The vaccine is formulated with an adjuvant, which is a substance that enhances the body's immune response to the vaccine. The adjuvant used in Audenz is MF59, an oil-in-water emulsion that has been used in other influenza vaccines.
Administration[edit | edit source]
The vaccine is administered as an intramuscular injection, typically in the upper arm. The dosing schedule for Audenz may vary depending on the age and health status of the individual receiving the vaccine. For most individuals, a two-dose series is recommended, with the second dose given 21 days after the first.
Efficacy and Safety[edit | edit source]
Clinical trials have shown that Audenz is effective in producing an immune response against the H5N1 virus. The most common side effects reported in clinical trials were mild and included pain at the injection site, headache, and muscle aches. Serious adverse events were rare.
Importance[edit | edit source]
The development of Audenz is significant because the H5N1 virus has the potential to cause a pandemic if it were to acquire the ability to spread easily from person to person. Vaccination with Audenz can help to protect individuals and reduce the spread of the virus in the event of an outbreak.
See Also[edit | edit source]
References[edit | edit source]
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