Avinza

From WikiMD's Wellness Encyclopedia

Avinza is a brand name for a morphine sulfate extended-release capsule used in the management of severe pain. It is an opioid analgesic, which means it is a type of medication that is used to relieve pain by acting on the central nervous system.

Medical Uses[edit | edit source]

Avinza is prescribed for the management of severe pain that requires continuous, around-the-clock treatment and for which alternative treatment options are inadequate. It is not intended for use on an as-needed basis for pain relief.

Mechanism of Action[edit | edit source]

Morphine, the active ingredient in Avinza, works by binding to opioid receptors in the brain and spinal cord. This binding inhibits the transmission of pain signals and alters the perception of pain, providing relief to the patient.

Dosage and Administration[edit | edit source]

Avinza is available in extended-release capsules, which are designed to release morphine slowly over a 24-hour period. The dosage is individualized based on the patient's prior opioid use, the severity of pain, and the patient's response to treatment. It is important to follow the prescribing physician's instructions carefully to avoid the risk of overdose or adverse effects.

Side Effects[edit | edit source]

Common side effects of Avinza include constipation, nausea, drowsiness, and dizziness. Serious side effects can include respiratory depression, hypotension, and addiction. Patients should be monitored for signs of misuse, abuse, and addiction.

Contraindications[edit | edit source]

Avinza is contraindicated in patients with significant respiratory depression, acute or severe bronchial asthma, and in those who have or are suspected of having paralytic ileus. It should also be avoided in patients with known hypersensitivity to morphine or any of the other ingredients in the formulation.

Warnings and Precautions[edit | edit source]

- Avinza carries a risk of addiction, abuse, and misuse, which can lead to overdose and death. - It should be used with caution in patients with a history of substance abuse or mental health disorders. - The use of Avinza with other central nervous system depressants, including alcohol, can increase the risk of respiratory depression and death.

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Contributors: Prab R. Tumpati, MD