BIM28163

From WikiMD's Wellness Encyclopedia

BIM28163 is a synthetic peptide that acts as a selective agonist for the somatostatin receptor subtype 5 (SSTR5). It is used primarily in research to study the physiological and pharmacological roles of somatostatin receptors, particularly in the context of endocrinology and neurobiology.

Structure and Properties[edit | edit source]

BIM28163 is a cyclic peptide, which contributes to its stability and specificity in binding to SSTR5. The exact amino acid sequence and structural details are proprietary and typically available through specialized biochemical databases and research publications.

Mechanism of Action[edit | edit source]

BIM28163 binds selectively to the SSTR5 receptor, mimicking the action of the natural ligand, somatostatin. Upon binding, it activates the receptor, leading to a cascade of intracellular events that can inhibit the release of various hormones and neurotransmitters. This makes it a valuable tool in studying the inhibitory effects of somatostatin on hormone secretion.

Applications in Research[edit | edit source]

BIM28163 is widely used in pharmacological and physiological research to:

Pharmacokinetics[edit | edit source]

The pharmacokinetic properties of BIM28163, including its absorption, distribution, metabolism, and excretion, are subjects of ongoing research. Its stability and selective receptor binding make it a useful compound for in vitro and in vivo studies.

Safety and Handling[edit | edit source]

As a research chemical, BIM28163 should be handled with care in a controlled laboratory environment. Proper safety protocols, including the use of personal protective equipment (PPE), should be followed to avoid any potential hazards.

Related Pages[edit | edit source]


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Contributors: Prab R. Tumpati, MD