BMP8A
BMP8A (Bone Morphogenetic Protein 8A) is a protein that in humans is encoded by the BMP8A gene. BMP8A is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors.
Function[edit | edit source]
BMP8A is a potent inducer of osteogenesis and chondrogenesis. This protein is expressed in a variety of tissues including the liver and uterus, and it may be involved in the development and normal function of the ovary and testis.
Clinical significance[edit | edit source]
Mutations in the BMP8A gene have been associated with a variety of diseases and conditions, including osteoporosis, rheumatoid arthritis, and certain types of cancer. Further research is needed to fully understand the role of BMP8A in these conditions.
Research[edit | edit source]
Research into BMP8A is ongoing, with studies focusing on its role in bone and cartilage development, as well as its potential as a therapeutic target for diseases such as osteoporosis and arthritis.
See also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD
