BMP8A

BMP8A (Bone Morphogenetic Protein 8A) is a protein that in humans is encoded by the BMP8A gene. BMP8A is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors.

Function

BMP8A is a potent inducer of osteogenesis and chondrogenesis. This protein is expressed in a variety of tissues including the liver and uterus, and it may be involved in the development and normal function of the ovary and testis.

Clinical significance

Mutations in the BMP8A gene have been associated with a variety of diseases and conditions, including osteoporosis, rheumatoid arthritis, and certain types of cancer. Further research is needed to fully understand the role of BMP8A in these conditions.

Research

Research into BMP8A is ongoing, with studies focusing on its role in bone and cartilage development, as well as its potential as a therapeutic target for diseases such as osteoporosis and arthritis.

See also

• Bone morphogenetic protein
• Transforming growth factor-beta
• Osteogenesis
• Chondrogenesis

References

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