BOH (psychedelic)

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BOH (psychedelic)

BOH, chemically known as 3,4-methylenedioxy-beta-hydroxyphenethylamine, is a lesser-known psychedelic drug and a structural analog of MDMA (3,4-methylenedioxymethamphetamine). Despite its structural similarity to MDMA, BOH is not widely known or used in the recreational drug scene, and its effects, pharmacology, and toxicity are not well-documented in scientific literature.

Chemistry[edit | edit source]

BOH belongs to the phenethylamine class of compounds, which is a broad family of substances that includes natural neurotransmitters such as dopamine and serotonin, as well as a variety of psychoactive drugs. The molecule of BOH features a methylenedioxy ring attached to a phenethylamine core, with a hydroxy group (–OH) attached to the beta position of the ethyl chain, distinguishing it from MDMA which has a methoxy group (–OCH3) in the same position.

Pharmacology[edit | edit source]

The pharmacological action of BOH is presumed to be primarily as a serotonin, dopamine, and norepinephrine releaser or reuptake inhibitor, similar to other compounds in its class. However, the exact mechanism of action remains speculative due to the lack of empirical research. The presence of the beta-hydroxy group may influence its affinity for various neurotransmitter transporters and receptors, potentially altering its psychoactive profile compared to MDMA.

Effects[edit | edit source]

The psychoactive effects of BOH are largely anecdotal and based on limited user reports. It is speculated to produce effects similar to other psychedelics and entactogens, such as enhanced sensory perception, euphoria, empathy, and altered states of consciousness. However, without systematic study, the extent, duration, and variability of these effects cannot be accurately described.

Safety and Toxicity[edit | edit source]

The safety profile and toxicity of BOH are virtually unknown. Given its structural similarity to MDMA, there may be risks of neurotoxicity, cardiotoxicity, and other adverse effects associated with amphetamines and phenethylamines. Potential users should be aware of the lack of information regarding its safety, and the substance should be approached with caution.

Legal Status[edit | edit source]

The legal status of BOH varies by country, but it may be controlled under analog acts or specific drug legislation due to its similarity to MDMA. In jurisdictions where analog laws are in place, possession, sale, or manufacture of BOH could be subject to legal penalties.

Conclusion[edit | edit source]

BOH represents a compound of interest within the field of psychoactive research chemicals, but its lack of widespread use and scientific study leaves many questions unanswered regarding its pharmacology, effects, and safety profile. Further research would be necessary to understand its potential risks and benefits.

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Contributors: Prab R. Tumpati, MD