BRD2

From WikiMD's Wellness Encyclopedia

Error creating thumbnail:
Protein BRD2 PDB 1x0j

BRD2

BRD2 is a gene that encodes the bromodomain-containing protein 2. This protein is involved in chromatin remodeling and transcriptional regulation. The BRD2 gene is located on chromosome 6 in humans.

Function[edit | edit source]

The BRD2 protein contains bromodomains, which are protein modules that recognize acetylated lysine residues on histone proteins. By binding to acetylated histones, BRD2 can regulate gene expression by influencing chromatin structure.

Role in Disease[edit | edit source]

Mutations in the BRD2 gene have been associated with certain diseases, including cancer and neurological disorders. Dysregulation of BRD2 expression can lead to abnormal cell growth and differentiation, contributing to the development of cancer. In neurological disorders, alterations in BRD2 function may affect neuronal development and function.

Research[edit | edit source]

Research on BRD2 has focused on understanding its role in gene regulation and disease pathogenesis. Studies have investigated the molecular mechanisms by which BRD2 influences chromatin structure and gene expression. Additionally, researchers are exploring the potential therapeutic implications of targeting BRD2 in disease treatment.

See also[edit | edit source]


Template:Chromatin-stub


This transcription-related article is a stub. You can help WikiMD by expanding it.

WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD