Bakuchiol

Bakuchiol is a meroterpene phenol abundant in seeds and leaves of the plant Psoralea corylifolia. It has been used in traditional Indian Ayurvedic medicine and Chinese medicine for its perceived medicinal properties.

Chemical Structure

Bakuchiol is a monoterpenoid phenol with a structure similar to retinol, a form of vitamin A. It is a pale-yellow solid that is soluble in organic solvents. Its chemical formula is C20H28O2.

Sources

Bakuchiol is primarily derived from the seeds and leaves of the plant Psoralea corylifolia, also known as babchi. This plant is native to India and other parts of Asia. Other sources of bakuchiol include the seeds of the Otholobium pubescens plant and the bark of the Zanthoxylum bungeanum tree.

Uses

Bakuchiol has been used in traditional Indian Ayurvedic medicine and Chinese medicine for centuries. It is believed to have anti-inflammatory, antioxidant, and antimicrobial properties. In recent years, it has gained popularity in the skincare industry as a plant-based alternative to retinol. Studies have shown that bakuchiol can stimulate collagen production and significantly improve the appearance of fine lines and wrinkles, similar to retinol, but without the associated side effects such as skin irritation and sensitivity to sunlight.

Safety and Side Effects

Bakuchiol is generally considered safe for topical use. However, like all skincare products, it may cause allergic reactions in some individuals. It is always recommended to do a patch test before using a new skincare product. Unlike retinol, bakuchiol does not increase the skin's sensitivity to sunlight, making it a safer option for daytime use.

Research

Research on bakuchiol is ongoing. Early studies suggest that it may have potential benefits in treating a variety of skin conditions, including acne, psoriasis, and atopic dermatitis. More research is needed to fully understand the potential benefits and risks of bakuchiol.

See Also

• Retinol
• Psoralea corylifolia
• Ayurvedic medicine
• Chinese medicine

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