Basaglar
Insulin glargine injection
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Basaglar is a brand name for insulin glargine, a long-acting insulin analog used in the management of diabetes mellitus. It is produced by Eli Lilly and Company in collaboration with Boehringer Ingelheim. Basaglar is designed to provide a steady level of insulin in the body over a 24-hour period, helping to control blood sugar levels in people with type 1 diabetes and type 2 diabetes.
Medical uses[edit | edit source]
Basaglar is indicated for the treatment of adults and pediatric patients with type 1 diabetes mellitus and adults with type 2 diabetes mellitus who require basal (long-acting) insulin for the control of hyperglycemia. It is typically administered once daily at the same time each day.
Mechanism of action[edit | edit source]
Insulin glargine, the active ingredient in Basaglar, is a recombinant human insulin analog. It has a prolonged duration of action due to its low solubility at physiological pH, which leads to the formation of microprecipitates in the subcutaneous tissue. These microprecipitates slowly release small amounts of insulin glargine, providing a steady level of insulin over 24 hours.
Side effects[edit | edit source]
Common side effects of Basaglar include hypoglycemia, injection site reactions, and allergic reactions. Less common but serious side effects can include severe hypoglycemia, hypokalemia, and hypersensitivity reactions.
Administration[edit | edit source]
Basaglar is administered via subcutaneous injection. It is available in a prefilled pen device, which allows for easy and accurate dosing. Patients are advised to rotate injection sites within the same region to reduce the risk of lipodystrophy.
Comparison with other insulins[edit | edit source]
Basaglar is biosimilar to Lantus, another insulin glargine product. Both medications have similar efficacy and safety profiles, but Basaglar is often chosen for its cost-effectiveness.
Related pages[edit | edit source]
- Diabetes mellitus
- Insulin
- Eli Lilly and Company
- Boehringer Ingelheim
- Hypoglycemia
- Type 1 diabetes
- Type 2 diabetes
References[edit | edit source]
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