Benzoylthiomethylecgonine

Benzoylthiomethylecgonine

Benzoylthiomethylecgonine is a chemical compound and a tropane alkaloid that is derived from the coca plant. It is most commonly known as the primary psychoactive ingredient in cocaine, a powerful stimulant drug.

Chemical Structure

Benzoylthiomethylecgonine is a complex molecule with a molecular formula of C17H21NO4. It consists of a benzoyl group attached to a tropane ring, with a methyl group and a thioester group attached to the nitrogen atom in the ring. The thioester group is what distinguishes benzoylthiomethylecgonine from other similar compounds, such as benzoylecgonine and methylecgonine.

Pharmacology

Benzoylthiomethylecgonine acts as a potent dopamine reuptake inhibitor, which means it blocks the reabsorption of the neurotransmitter dopamine in the brain. This leads to an increase in the amount of dopamine in the synaptic cleft, which in turn leads to increased stimulation of dopamine receptors. This is believed to be the primary mechanism by which cocaine produces its characteristic euphoric and stimulant effects.

Toxicology

The use of cocaine, and by extension benzoylthiomethylecgonine, can lead to a number of serious health risks. These include cardiovascular disease, stroke, and addiction. Chronic use can also lead to significant damage to the nasal septum due to the vasoconstrictive effects of the drug.

Legal Status

In most jurisdictions, benzoylthiomethylecgonine is classified as a controlled substance due to its potential for abuse and addiction. This includes the United States, where it is classified as a Schedule II drug under the Controlled Substances Act.

See Also

• Cocaine
• Tropane alkaloids
• Controlled Substances Act

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