Glycopyrronium bromide/formoterol
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Glycopyrronium bromide/formoterol is a combination medication used in the management of COPD. It contains two active ingredients: Glycopyrronium bromide and Formoterol.
Etymology[edit | edit source]
The name "Glycopyrronium bromide" is derived from its chemical structure, which includes a glycopyrrolate moiety and a bromide ion. The name "Formoterol" is derived from its chemical structure, which includes a formamide moiety and a phenol group.
Pharmacology[edit | edit source]
Glycopyrronium bromide is a Muscarinic antagonist, which works by blocking the action of acetylcholine on muscarinic receptors in the lungs, thereby reducing bronchoconstriction. Formoterol is a long-acting beta2-adrenoceptor agonist (LABA), which works by stimulating beta2-adrenoceptors in the lungs, thereby causing bronchodilation.
Clinical Use[edit | edit source]
Glycopyrronium bromide/formoterol is used as a maintenance treatment for COPD. It is not used for the relief of acute symptoms, i.e., as a rescue therapy. The medication is administered via inhalation.
Side Effects[edit | edit source]
Common side effects of glycopyrronium bromide/formoterol include dry mouth, nasopharyngitis, and upper respiratory tract infection. Less common side effects include urinary retention, blurred vision, and palpitations.
Related Terms[edit | edit source]
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Contributors: Prab R. Tumpati, MD
