Bismuth subcitrate/metronidazole/tetracycline

Bismuth Subcitrate/Metronidazole/Tetracycline is a combination medication used primarily in the treatment of peptic ulcer disease caused by Helicobacter pylori. This medication combines the properties of three different drugs: bismuth subcitrate, metronidazole, and tetracycline.

Composition

The medication is composed of three active ingredients:

• Bismuth subcitrate: A compound used as an antacid and bismuth source, it helps to protect the stomach lining and is also believed to kill H. pylori bacteria.
• Metronidazole: An antibiotic that works by stopping the growth of bacteria and protozoa.
• Tetracycline: A broad-spectrum antibiotic that stops the growth of bacteria by preventing them from producing proteins they need to survive.

Indications

This combination medication is used to treat certain types of stomach ulcers (specifically, those caused by H. pylori infection). It is usually used in combination with a proton pump inhibitor.

Side Effects

Like all medications, bismuth subcitrate/metronidazole/tetracycline can cause side effects. These may include nausea, diarrhea, stomach cramps, and changes in taste. More serious side effects can include signs of a new infection, severe stomach or abdominal pain, and dark urine.

Contraindications

This medication should not be used by individuals who are allergic to bismuth subcitrate, metronidazole, tetracycline, or any other ingredient in the product. It is also contraindicated in individuals with kidney disease, liver disease, or certain blood disorders.

Interactions

Bismuth subcitrate/metronidazole/tetracycline can interact with other medications, including anticoagulants, atovaquone, and certain oral typhoid vaccines. It is important to inform healthcare providers of all medications being taken before starting this medication.

See Also

• Peptic ulcer disease
• Helicobacter pylori
• Antibiotics
• Proton pump inhibitor