Blocking antibody
Blocking antibody is a type of antibody that prevents the binding of an antigen to its specific receptor on the surface of a cell. This can inhibit or block the biological effect of the antigen.
Mechanism of Action[edit | edit source]
Blocking antibodies work by binding to the same epitope on an antigen that the receptor would normally bind to. This prevents the antigen from binding to the receptor and triggering a response. This can be beneficial in situations where the antigen would otherwise cause a harmful response, such as in allergic reactions or autoimmune diseases.
Uses in Medicine[edit | edit source]
Blocking antibodies have a number of potential uses in medicine. They can be used to treat a variety of conditions, including cancer, inflammatory diseases, and infectious diseases. For example, they can be used to block the action of cytokines, which are proteins that can cause inflammation and other immune responses. They can also be used to block the action of growth factors, which can promote the growth of cancer cells.
Research and Development[edit | edit source]
Research is ongoing into the development of new blocking antibodies for use in medicine. This includes research into the design and production of blocking antibodies, as well as clinical trials to test their safety and effectiveness. The development of new blocking antibodies has the potential to lead to new treatments for a wide range of diseases.
See Also[edit | edit source]
- Antibody
- Antigen
- Epitope
- Receptor
- Cytokine
- Growth factor
- Cancer
- Inflammatory diseases
- Infectious diseases
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Contributors: Prab R. Tumpati, MD