Bracht Wachter bodies

Bracht-Wachter Bodies

Bracht-Wachter bodies are a histopathological finding observed in the placenta, particularly in cases of placental infarction. These bodies are named after the German pathologists Erich Bracht and Hermann Wachter, who first described them. They are considered an important diagnostic feature in the study of placental pathology.

Description

Bracht-Wachter bodies are small, round, eosinophilic structures found within the intervillous space of the placenta. They are composed of fibrin and necrotic trophoblastic tissue. These bodies are typically associated with areas of placental infarction, where there is localized tissue death due to inadequate blood supply.

Pathogenesis

The formation of Bracht-Wachter bodies is linked to the process of placental infarction. When blood flow to a portion of the placenta is compromised, it leads to ischemia and subsequent necrosis of the affected tissue. The necrotic tissue, along with fibrin deposition, forms the characteristic Bracht-Wachter bodies. These bodies can be seen in histological sections stained with hematoxylin and eosin (H&E).

Clinical Significance

The presence of Bracht-Wachter bodies in the placenta is indicative of placental insufficiency and can be associated with adverse pregnancy outcomes. Conditions such as preeclampsia, intrauterine growth restriction (IUGR), and stillbirth may be linked to the presence of these bodies. Therefore, their identification can provide valuable information in the assessment of placental function and fetal health.

Diagnosis

Diagnosis of Bracht-Wachter bodies is made through histopathological examination of the placenta. A pathologist will examine tissue sections under a microscope, looking for the characteristic eosinophilic bodies within the intervillous space. The presence of these bodies, along with other histological findings, can help in diagnosing placental infarction and assessing its extent.

Historical Background

Erich Bracht and Hermann Wachter were pioneering pathologists who contributed significantly to the understanding of placental pathology. Their work in the early 20th century laid the foundation for modern placental histopathology, and the identification of Bracht-Wachter bodies remains a testament to their contributions.

Also see

• Placental Infarction
• Preeclampsia
• Intrauterine Growth Restriction
• Stillbirth
• Histopathology