Brachy therapy

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Brachy therapy

Brachytherapy is a form of radiotherapy where a sealed radiation source is placed inside or next to the area requiring treatment. Brachytherapy is commonly used as an effective treatment for cervical cancer, prostate cancer, breast cancer, and skin cancer, and can also be used to treat tumors in many other body sites.

Overview[edit | edit source]

Brachytherapy involves the precise placement of radiation sources directly at the site of the cancerous tumor. This technique allows for a high dose of radiation to be applied to a small area, minimizing the dose to the surrounding healthy tissues. There are two main types of brachytherapy: temporary and permanent. In temporary brachytherapy, the radiation sources are placed for a set duration before being removed. In contrast, permanent brachytherapy, also known as seed implantation, involves placing small radioactive seeds in or near the tumor permanently, where they gradually decay and stop giving off radiation.

Types of Brachytherapy[edit | edit source]

High-Dose-Rate (HDR) Brachytherapy[edit | edit source]

HDR brachytherapy involves placing very high doses of radiation in the tumor for a short period of time. The radiation source is typically inserted for a few minutes at a time. This process may be repeated several times.

Low-Dose-Rate (LDR) Brachytherapy[edit | edit source]

In LDR brachytherapy, the radiation source is placed in the tumor site for a longer period, ranging from several hours to several days. The radiation emitted is at a lower dose rate compared to HDR brachytherapy.

Pulsed-Dose-Rate (PDR) Brachytherapy[edit | edit source]

PDR brachytherapy is a variation of HDR brachytherapy, where the radiation is delivered in pulses, typically once an hour, mimicking the overall dose rate of LDR brachytherapy.

Applications[edit | edit source]

Brachytherapy is used to treat several types of cancer, including:

It is also used in some cases to prevent the recurrence of cancer after the primary treatment has been completed.

Advantages[edit | edit source]

The main advantage of brachytherapy over external beam radiation therapy (EBRT) is the ability to deliver a high dose of radiation to a more localized area, with reduced exposure to surrounding healthy tissues. This can lead to fewer side effects and a shorter treatment time.

Procedure[edit | edit source]

The specific procedure for brachytherapy varies depending on the cancer being treated and the type of brachytherapy being used. Generally, the process involves: 1. Planning: Imaging tests are used to determine the exact location and size of the tumor. 2. Placement: The radiation source is placed in or near the tumor using needles, catheters, or a specialized applicator. 3. Treatment: Radiation is delivered according to the treatment plan. 4. Removal: In temporary brachytherapy, the radiation source is removed after the treatment.

Risks and Side Effects[edit | edit source]

While brachytherapy is generally safe, it can cause side effects, including fatigue, skin irritation, and in some cases, more serious complications depending on the treatment site. Long-term side effects may include fibrosis, damage to nearby organs, and the risk of developing a second cancer.

Conclusion[edit | edit source]

Brachytherapy is a critical component of modern cancer treatment, offering a targeted approach that can minimize damage to healthy tissues. Its use in treating various types of cancer underscores its versatility and effectiveness as a treatment modality.

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Contributors: Prab R. Tumpati, MD