Brodmann area 16

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Brodmann area 16 is a region of the brain defined based on its cytoarchitectonic characteristics. It is also known as the insula area 16, as it corresponds to a portion of the insular cortex. This area is named after its discoverer, Korbinian Brodmann, a German neurologist who first defined and numbered the areas of the brain based on their cellular structure and organization.

Anatomy[edit | edit source]

Brodmann area 16 is located within the cerebral cortex, the outermost layer of the brain. It is part of the insular cortex, a region of the brain located within the lateral sulcus, the deep fold that separates the frontal lobe and parietal lobe from the temporal lobe. The insular cortex is believed to be involved in consciousness and plays a role in diverse functions usually linked to emotion or the regulation of the body's homeostasis.

Function[edit | edit source]

The exact function of Brodmann area 16 is not fully understood. However, it is thought to be involved in various functions related to emotion, perception, motor control, self-awareness, cognitive functioning, and interpersonal experience. In particular, it is involved in the perception of emotions in facial stimuli, the generation of compassionate emotions, and the integration of sensory information from the body.

Clinical significance[edit | edit source]

Alterations or damage to Brodmann area 16 can lead to a variety of neurological and psychiatric conditions. For example, it has been implicated in schizophrenia, autism, and anxiety disorders. Further research is needed to fully understand the role of this area in these conditions and to develop potential treatments.

See also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD