Buccal swab
Buccal swab
A buccal swab is a method used to collect DNA from the cells on the inside of a person's cheek. This non-invasive procedure is commonly used in various fields such as genetics, forensics, and medical diagnostics.
Procedure[edit | edit source]
The procedure for obtaining a buccal swab is simple and painless. A sterile cotton swab or a small brush is rubbed against the inside of the cheek to collect epithelial cells. These cells contain DNA that can be analyzed for various purposes.
Applications[edit | edit source]
Genetic Testing[edit | edit source]
Buccal swabs are frequently used in genetic testing to identify genetic disorders, determine paternity, and for ancestry research. The DNA collected from the swab is analyzed in a laboratory to provide insights into an individual's genetic makeup.
Forensic Science[edit | edit source]
In forensic science, buccal swabs are used to collect DNA evidence from suspects and crime scenes. This DNA can be compared to DNA found at a crime scene to help identify or eliminate suspects.
Medical Diagnostics[edit | edit source]
In medical diagnostics, buccal swabs are used to detect genetic mutations that may indicate a predisposition to certain diseases. This can help in early diagnosis and personalized treatment plans.
Advantages[edit | edit source]
Buccal swabs offer several advantages over other methods of DNA collection:
- Non-invasive and painless
- Easy to perform
- Cost-effective
- Can be done at home or in a clinical setting
Limitations[edit | edit source]
While buccal swabs are highly effective, they do have some limitations:
- The amount of DNA collected may be insufficient for some types of analysis
- Contamination from food, drink, or other substances can affect the quality of the sample
Related Pages[edit | edit source]
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD