Buccal swab

From WikiMD's Wellness Encyclopedia

Buccal swab

A buccal swab is a method used to collect DNA from the cells on the inside of a person's cheek. This non-invasive procedure is commonly used in various fields such as genetics, forensics, and medical diagnostics.

Procedure[edit | edit source]

The procedure for obtaining a buccal swab is simple and painless. A sterile cotton swab or a small brush is rubbed against the inside of the cheek to collect epithelial cells. These cells contain DNA that can be analyzed for various purposes.

Applications[edit | edit source]

Genetic Testing[edit | edit source]

Buccal swabs are frequently used in genetic testing to identify genetic disorders, determine paternity, and for ancestry research. The DNA collected from the swab is analyzed in a laboratory to provide insights into an individual's genetic makeup.

Forensic Science[edit | edit source]

In forensic science, buccal swabs are used to collect DNA evidence from suspects and crime scenes. This DNA can be compared to DNA found at a crime scene to help identify or eliminate suspects.

Medical Diagnostics[edit | edit source]

In medical diagnostics, buccal swabs are used to detect genetic mutations that may indicate a predisposition to certain diseases. This can help in early diagnosis and personalized treatment plans.

Advantages[edit | edit source]

Buccal swabs offer several advantages over other methods of DNA collection:

  • Non-invasive and painless
  • Easy to perform
  • Cost-effective
  • Can be done at home or in a clinical setting

Limitations[edit | edit source]

While buccal swabs are highly effective, they do have some limitations:

  • The amount of DNA collected may be insufficient for some types of analysis
  • Contamination from food, drink, or other substances can affect the quality of the sample

Related Pages[edit | edit source]

See Also[edit | edit source]

Contributors: Prab R. Tumpati, MD