Buschke disease

Buschke Disease also known as Scleredema Adultorum of Buschke is a rare, progressive connective tissue disorder characterized by thickening and hardening of the skin, typically affecting the upper back, neck, and shoulders. It was first described by the German dermatologist Abraham Buschke in 1902.

Etiology

The exact cause of Buschke Disease is unknown. However, it is often associated with diabetes mellitus, especially in cases where the disease is chronic. Other potential triggers include infections, particularly streptococcal infections, and monoclonal gammopathy.

Symptoms

The primary symptom of Buschke Disease is the gradual thickening and hardening of the skin, which can lead to restricted movement. The skin may also appear shiny or waxy. In some cases, patients may experience mild to moderate pain or discomfort. The disease typically affects the upper back, neck, and shoulders, but can also involve the face, arms, and upper chest.

Diagnosis

Diagnosis of Buschke Disease is primarily based on the clinical presentation and physical examination. A skin biopsy may be performed to confirm the diagnosis. Other diagnostic tests may include blood tests to rule out other conditions, and imaging studies such as magnetic resonance imaging (MRI) to assess the extent of the disease.

Treatment

There is currently no cure for Buschke Disease. Treatment is primarily aimed at managing symptoms and improving the patient's quality of life. This may include physical therapy to improve mobility, and medications such as corticosteroids to reduce inflammation. In severe cases, immunosuppressive drugs may be used.

Prognosis

The prognosis for individuals with Buschke Disease varies. Some individuals may experience a slow progression of the disease over many years, while others may have a more rapid course. The disease is not typically life-threatening, but can significantly impact the individual's quality of life due to physical limitations and discomfort.

See also

• Connective tissue disease
• Dermatology
• Diabetes mellitus