Butamirate

Butamirate

Butamirate is a non-opioid antitussive agent, primarily used in the treatment of cough. It is a centrally acting cough suppressant, which means it acts on the central nervous system to reduce the urge to cough. Butamirate is marketed under various brand names across the world, including Sinecod, Mucosolvan, and Omnitus.

Pharmacology

Butamirate works by suppressing the cough reflex in the medulla oblongata, a part of the brain that controls coughing. It also has a moderate bronchodilating effect, which helps to open up the airways in the lungs and thus makes breathing easier. Unlike opioid antitussives, Butamirate does not cause respiratory depression or dependence.

Medical Uses

Butamirate is used to treat both acute and chronic coughs. It is particularly effective in treating non-productive (dry) coughs, which are often caused by viral infections such as the common cold or influenza. Butamirate can also be used to treat coughs associated with chronic conditions such as asthma or chronic obstructive pulmonary disease (COPD).

Side Effects

Like all medications, Butamirate can cause side effects, although not everyone gets them. Common side effects include nausea, vomiting, diarrhea, and dizziness. In rare cases, Butamirate can cause allergic reactions, including anaphylaxis, a severe and potentially life-threatening allergic reaction.

Contraindications

Butamirate is contraindicated in patients with a known hypersensitivity to the drug or any of its components. It should also be used with caution in patients with severe liver or kidney disease, as these conditions can affect the way the body metabolizes the drug.

See Also

• Antitussive
• Cough
• Medulla oblongata
• Respiratory depression