Butonitazene
A synthetic opioid analgesic
Butonitazene is a synthetic opioid analgesic that belongs to the benzimidazole family of compounds. It is structurally related to other opioids such as etazene and metonitazene. Butonitazene is known for its potent analgesic effects, which are mediated through its action as an agonist at the mu-opioid receptor.
Chemical structure and properties[edit | edit source]
Butonitazene is characterized by its complex chemical structure, which includes a benzimidazole core. The chemical formula of Butonitazene is C23H30N2O2. The presence of the diethylaminoethyl group and the phenylpiperidine moiety are significant for its pharmacological activity.
Pharmacology[edit | edit source]
Butonitazene acts primarily as a mu-opioid receptor agonist. This receptor is part of the opioid receptor family, which also includes the delta-opioid receptor and the kappa-opioid receptor. Activation of the mu-opioid receptor by Butonitazene leads to analgesia, euphoria, and respiratory depression, which are common effects associated with opioid use.
Medical use[edit | edit source]
Butonitazene has been investigated for its potential use as an analgesic in clinical settings. However, due to its potency and the risk of adverse effects such as respiratory depression, its use is limited and it is not widely available for medical use.
Adverse effects[edit | edit source]
The adverse effects of Butonitazene are similar to those of other opioids. These include:
- Respiratory depression
- Sedation
- Nausea and vomiting
- Constipation
- Risk of dependence and addiction
Legal status[edit | edit source]
Due to its potential for abuse and addiction, Butonitazene is classified as a controlled substance in many countries. Its legal status varies, and it is important to consult local regulations regarding its use and distribution.
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