Buttock cell

A Sézary cell, a type of buttock cell, under a microscope.

A buttock cell is a term used in hematology to describe a specific morphological appearance of certain lymphocytes that are often seen in various hematological disorders. These cells are characterized by their distinctive shape, which resembles the contour of human buttocks. This appearance is typically observed in certain types of leukemia and lymphoma, particularly in Sézary syndrome.

Morphology

Buttock cells are a type of atypical lymphocyte that exhibit a characteristic indentation or cleft in the nucleus, giving them their unique shape. The cytoplasm of these cells is usually abundant and may appear basophilic. The nuclear chromatin is often coarse, and nucleoli may be present.

Clinical Significance

The presence of buttock cells can be an important diagnostic feature in the evaluation of certain hematological conditions. They are most commonly associated with:

• Sézary syndrome: A type of cutaneous T-cell lymphoma where buttock cells, also known as Sézary cells, are found in the peripheral blood.
• Mycosis fungoides: Another form of cutaneous T-cell lymphoma where similar cells may be observed.
• Other lymphoproliferative disorders: Buttock cells may occasionally be seen in other conditions, although they are not as specific.

Diagnostic Techniques

The identification of buttock cells is typically performed through peripheral blood smear examination using light microscopy. In some cases, additional techniques such as flow cytometry or immunohistochemistry may be employed to further characterize these cells and aid in diagnosis.

Related Pages

• Lymphocyte
• Leukemia
• Lymphoma
• Sézary syndrome
• Mycosis fungoides