Butyrylnorfentanyl

Butyrylnorfentanyl

Butyrylnorfentanyl is a potent synthetic opioid that is an analog of fentanyl. It was first identified in seized drug samples in Europe in 2016 and has been associated with a number of overdose deaths.

Chemistry

Butyrylnorfentanyl, also known as N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl] butanamide, is a fentanyl analog, meaning it has a similar chemical structure to fentanyl but with some modifications. The primary difference is the addition of a butyryl group to the nitrogen atom in the piperidine ring of the fentanyl molecule.

Pharmacology

Like other opioids, butyrylnorfentanyl acts on the mu-opioid receptor in the brain to produce its effects. It is believed to be less potent than fentanyl, but more potent than morphine. However, due to its illicit nature, exact potency and effects can vary greatly depending on the batch.

Legal Status

Butyrylnorfentanyl is a controlled substance in many countries due to its potential for abuse and the health risks associated with its use. In the United States, it is a Schedule I controlled substance, meaning it has no accepted medical use and a high potential for abuse.

Health Risks

The use of butyrylnorfentanyl, like other synthetic opioids, carries a high risk of overdose due to its potency. Symptoms of overdose can include slowed breathing, loss of consciousness, and death. There is also a risk of dependence and withdrawal symptoms with prolonged use.

See Also

• Fentanyl
• Opioid
• Opioid overdose
• Controlled Substances Act