CD31

CD31, also known as PECAM-1 (Platelet Endothelial Cell Adhesion Molecule), is a type of protein that is encoded by the PECAM1 gene in humans. It is a member of the immunoglobulin superfamily and is primarily found on the surface of endothelial cells and platelets.

Function

CD31 plays a crucial role in removing aged neutrophils from the body. It is also involved in the process of leukocyte transmigration, angiogenesis, and integrin activation. It is a key player in the process of cell-cell adhesion, a function that is supported by its localization to areas of cell-cell contact.

Clinical significance

CD31 has been used as a endothelial cell marker in histological staining. It is also used in medical research to identify and isolate endothelial cells. In addition, it has been associated with certain types of cancer, including melanoma and breast cancer.

See also

• CD34
• CD105
• CD146

External links

• PECAM1 at the US National Library of Medicine Medical Subject Headings (MeSH)

CD31 Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.

Translate to: East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski