CD57
CD57, also known as HNK-1 or Leu-7, is a carbohydrate antigen present on various types of immune cells. It is used as a marker for certain types of lymphocytes, and its expression is associated with specific stages of cell differentiation and activation.
Function[edit | edit source]
CD57 is expressed on the surface of natural killer cells, T lymphocytes, and some B lymphocytes. It is involved in cell-cell adhesion, cell migration, and modulating cell signaling. CD57+ cells have been shown to have potent cytotoxic activity and are involved in the immune response to viral infections and cancer.
Clinical significance[edit | edit source]
In the clinical setting, CD57 is used as a marker for certain types of lymphoma and neuroendocrine tumors. It is also used to monitor the immune status of individuals with chronic Lyme disease, as the number of CD57+ cells has been shown to correlate with disease activity.
See also[edit | edit source]
References[edit | edit source]
| CD57 Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
