CD79a
CD79a is a protein that in humans is encoded by the CD79A gene. It is also known as Ig-alpha (Immunoglobulin-alpha) and is involved in the development and functioning of B cells, a type of white blood cell.
Function[edit | edit source]
CD79a and CD79b proteins are necessary for initiating the signal transduction cascade that is activated by binding of antigen to the B cell antigen receptor (BCR) complex. These proteins also are necessary for B cell development. Defects in the CD79A gene can result in agammaglobulinemia-3.
Clinical significance[edit | edit source]
Mutations in the CD79A gene are associated with agammaglobulinemia-3, a condition that affects the immune system and results in a lack of B cells and immunoglobulins, leading to recurrent bacterial infections.
Interactions[edit | edit source]
CD79a has been shown to interact with CD79B, Lyn, and Syk.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
- Human CD79A gene details page in the NCBI/NLM/NIH Gene database
| CD79a Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
