CLEC2D
CLEC2D
CLEC2D is a gene that encodes a C-type lectin domain family 2 member D protein in humans. This gene is located on chromosome 12 and is involved in immune response regulation.
Function[edit | edit source]
The CLEC2D protein is a type II transmembrane receptor that is expressed on natural killer (NK) cells and some T cells. It plays a role in modulating immune responses by interacting with ligands on target cells.
Structure[edit | edit source]
The CLEC2D protein contains a C-type lectin domain, which is characteristic of proteins involved in immune recognition. This domain allows the protein to bind to specific ligands and mediate cellular interactions.
Clinical Significance[edit | edit source]
Mutations in the CLEC2D gene have been associated with certain autoimmune diseases and immune system dysregulation. Understanding the function of this gene may provide insights into the development of novel therapeutic strategies for immune-related disorders.
Interactions[edit | edit source]
The CLEC2D protein has been shown to interact with various ligands on target cells, including certain glycoproteins and carbohydrates. These interactions are crucial for the activation of immune responses and the regulation of immune cell functions.
References[edit | edit source]
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