CNKSR2

CNKSR2 (Connector Enhancer of Kinase Suppressor of Ras 2) is a protein that in humans is encoded by the CNKSR2 gene. This protein is part of the signal transduction pathway, which is a complex system of communication that governs basic cellular functions and coordinates cell actions.

Function

The CNKSR2 protein is involved in the transmission of signals within cells. It is a scaffold protein, meaning it helps to organize and position other proteins. Specifically, it interacts with several other proteins involved in signal transduction, including Ras, Raf, and MAPK.

Clinical significance

Mutations in the CNKSR2 gene have been associated with several neurological disorders. These include intellectual disability, epilepsy, and non-syndromic X-linked intellectual disability.

See also

• CNKSR1
• Signal transduction
• X-linked intellectual disability

External links

• CNKSR2 at the National Center for Biotechnology Information