CPNE7

CPNE7 (Copine VII) is a protein that in humans is encoded by the CPNE7 gene. It is a member of the copine family, a group of proteins characterized by the presence of two C2 domains and one von Willebrand factor A (VWA) domain.

Function

The CPNE7 gene encodes a calcium-dependent membrane-binding protein which is primarily expressed in the brain. It has been suggested that this protein may have a role in the regulation of synaptic plasticity in neuronal cells.

Clinical significance

Alterations in the CPNE7 gene have been associated with various neurological disorders, including schizophrenia and bipolar disorder. However, further research is needed to fully understand the role of CPNE7 in these conditions.

See also

• Copine
• C2 domain
• Von Willebrand factor A domain

External links

• CPNE7 at the NCBI Gene