CUTL1

CUTL1 (also known as CUX1) is a gene that encodes a protein involved in the regulation of cell growth and differentiation. The protein is a transcription factor, which means it helps control the activity of other genes.

Function

The CUTL1 gene provides instructions for making a protein that plays a crucial role in controlling the growth and division (proliferation) of cells, the process by which cells mature to carry out specific functions (differentiation), and the self-destruction of cells (apoptosis). The CUTL1 protein can be found in the nucleus of cells, where it binds to specific regions of DNA and helps control the activity of particular genes.

Clinical significance

Mutations in the CUTL1 gene have been associated with a variety of cancers, including breast cancer, ovarian cancer, and acute myeloid leukemia. These mutations can lead to the production of a CUTL1 protein that is abnormally short and nonfunctional, which can disrupt the normal regulation of cell growth and division and lead to the development of cancer.

Research

Research is ongoing to better understand the role of the CUTL1 gene in cell growth and differentiation, and how mutations in this gene contribute to the development of cancer. This research may lead to the development of new treatments for cancers associated with mutations in the CUTL1 gene.

File:CUTL1 gene location.png

Location of the CUTL1 gene on chromosome 7.

See also

• Transcription factor
• Gene
• Cancer
• Breast cancer
• Ovarian cancer
• Acute myeloid leukemia

‎

---

Translate: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, தமிழ், తెలుగు, Urdu, ಕನ್ನಡ, Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, বাংলা
European español, Deutsch, français, Greek, português do Brasil, polski, română, русский, Nederlands, norsk, svenska, suomi, Italian
Middle Eastern & African عربى, Turkish, Persian, Hebrew, Afrikaans, isiZulu, Kiswahili,
Other Bulgarian, Hungarian, Czech, Swedish, മലയാളം, मराठी, ਪੰਜਾਬੀ, ગુજરાતી, Portuguese, Ukrainian