CXC

CXC is a type of chemokine that plays a significant role in the body's immune system. It is part of the larger family of CXC chemokines, which are small proteins that act as signaling molecules to attract white blood cells to sites of inflammation or injury.

Function

CXC chemokines are primarily responsible for the movement of neutrophils, a type of white blood cell, towards the site of inflammation. They do this by binding to specific receptors on the surface of the neutrophils, which triggers a response that leads to the movement of the cells.

Structure

The structure of CXC chemokines is characterized by four cysteine residues, two of which are separated by any amino acid, hence the name "CXC". This structure is crucial for the function of these chemokines, as it allows them to bind to their specific receptors.

Role in Disease

CXC chemokines have been implicated in a number of diseases, including cancer, autoimmune diseases, and inflammatory diseases. In cancer, they can promote the growth and spread of tumors by attracting neutrophils to the tumor site. In autoimmune diseases, they can contribute to the inflammation and damage caused by the immune system's attack on the body's own tissues. In inflammatory diseases, they can exacerbate the inflammation and damage caused by the immune response.

See Also

• Chemokine
• Neutrophil
• Inflammation
• Cancer
• Autoimmune diseases
• Inflammatory diseases

CXC Resources
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