Cadexomer iodine

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A topical antimicrobial agent used in wound care



Cadexomer Iodine[edit | edit source]

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Cadexomer iodine gel applied to a wound

Cadexomer iodine is a topical antimicrobial agent used primarily in the treatment of chronic wounds, such as venous leg ulcers, pressure ulcers, and diabetic foot ulcers. It is composed of a hydrophilic, cross-linked modified starch matrix that contains iodine, which is slowly released as the matrix absorbs wound exudate.

Mechanism of Action[edit | edit source]

Cadexomer iodine works by releasing iodine in a controlled manner, which provides a sustained antimicrobial effect. The iodine is effective against a broad spectrum of microorganisms, including bacteria, fungi, and viruses. The starch matrix absorbs exudate, which helps to maintain a moist wound environment conducive to healing.

Clinical Uses[edit | edit source]

Cadexomer iodine is indicated for use in the management of exuding wounds. It is particularly useful in wounds that are infected or at risk of infection. The product is available in various forms, including ointments, gels, and dressings, allowing for flexibility in application depending on the wound type and location.

Application[edit | edit source]

The application of cadexomer iodine involves cleaning the wound and applying the product directly to the wound bed. It is important to cover the treated area with an appropriate secondary dressing to maintain the product in place and to manage exudate. The frequency of dressing changes depends on the level of exudate and the clinical condition of the wound.

Advantages[edit | edit source]

Cadexomer iodine offers several advantages in wound care:

  • Broad-spectrum antimicrobial activity: Effective against a wide range of pathogens.
  • Sustained release of iodine: Provides prolonged antimicrobial action.
  • Exudate management: Absorbs wound exudate, reducing the risk of maceration.
  • Moist wound environment: Promotes optimal conditions for wound healing.

Precautions and Contraindications[edit | edit source]

While cadexomer iodine is generally well-tolerated, there are some precautions and contraindications to consider:

  • Allergy to iodine: Patients with known iodine sensitivity should not use this product.
  • Thyroid disorders: Use with caution in patients with thyroid dysfunction due to potential iodine absorption.
  • Pregnancy and lactation: Consult a healthcare professional before use.

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Contributors: Prab R. Tumpati, MD